ABSTRACT
Objetivos: Determinar las características epidemiológicas de los pacientes con diagnóstico de Tuberculosis (TB) que asistieron en el período comprendido entre el 01 de mayo de 2010 y 30 de abril de 2013 al Hospital Tránsito Cáceres de Allende (HTCA) de Córdoba Argentina. Materiales y métodos: Estudio descriptivo, observacional y prospectivo, en 106 pacientes mayores de 15 años. Resultados: Se observó mayor frecuencia entre los 15 -35 años (48%), 55% fueron masculinos, 90% fueron argentinos, la mortalidad fue del 4%; el 50% con ocupación estable, comorbilidades: Diabetes mellitus 19% y VIH 1%, tabaquismo 61%, alcohol 23% y drogas ilícitas 22%, IMC
Objectives: To determine the epidemiologic characteristics of patients diagnosed with TB who attended the hospital Transito Caceres de Allende of Cordoba, Argentina in the period from May 1st, 2010 to April 30th, 2013. Materials and methods: Descriptive, observational and prospective study in 106 patients older than 15 years old. Results: There was a higher frequency on the 15 to 35 years old (48%), male 55%, Argentine 90%, case fatality 4%, stable employment 50%, comorbidities: diabetes mellitus 19% , HIV 1%, tobacco smoking 61%, alcohol addiction 23%, consumption of illegal drugs 22%, BMI lower than 21: 63%. Bacteriologic diagnosis: positive direct smear microscopy 73%, positive culture 66% and pathologic histology 20%, treatment adherence: adherence 97%, healed 92 %, self administered treatment 96%, MDR-TB 3%. Forms of presentations: pulmonary TB 72%, extrapulmonary TB 28%. Radiological abnormalities: unilateral infiltrates with cavity 27%, unilateral without cavity 20%. Laboratory tests: Leukocytosis 15%, high erythrocyte sedimentation 82%, Adverse Drug Reactions: hepatoxicity 4%. Conclusions: Male young adult is more likely to become ill. Diabetes, HIV and BMI < 21 must prompt screening studies in symptomatic patients. Smoking habit, unemployment and bad social economics conditions are positive epidemiologic factors. Usual laboratory data is nonspecific but can provide some guiding. Thorax (chest) radiography, microscopy and culture are accessible diagnostic resources. MDR-TB is not yet a relevant problem in our hospital. Treatment related hepatotoxicity did not require interruption of therapy. Self administered treatment strategy with high adherence, low dropout and high healing rate indicate a big success of the program.